Dimethylformamide → 4-(Chloromethyl)-2-(methylthio)pyrimidine

HRID 805340Notes

Reaction equation

[CH3:15][N:16]([CH3:17])[CH:18]=[O:19].[CH3:1][S:2][c:3]1[n:4][cH:5][cH:6][c:7]([CH2:9][OH:10])[n:8]1.[Cl:20][CH2:21][Cl:22].[S:11]([Cl:12])([Cl:13])=[O:14]>>[CH3:1][S:2][c:3]1[n:4][cH:5][cH:6][c:7]([CH2:9][Cl:13])[n:8]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 14270868(2-(Methylthio)pyrimidin-4-yl)methanol

Product 1

HCID 552634394-(Chloromethyl)-2-(methylthio)pyrimidine

Sources & evidence

ORD record: ord-78b872c1515a4b168f237b6007fae928
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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