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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80567Generated: October 27, 2026

HCID 44119394, compound → 3-[9-(2-chloro-3,6-difluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b][1,4]diazepin-2-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide

https://huagongshe.com/reaction/80567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 44119394HCID 44119394—
Reactant2-Bromo-9-(2-chloro-3,6-difluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b][1,4]diazepineHCID 86659430—
Product3-[9-(2-chloro-3,6-difluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b][1,4]diazepin-2-yl]-N-[2-(morpholin-4-yl)ethyl]benzamideHCID 67008168—

Reaction Steps

The entitled compound can be prepared from 2-Bromo-9-(2-chloro-3,6-difluorobenzyl)-6,7,8,9-tetrahydro-5H-pyrazino[2,3-b][1,4]diazepine and 3-(2-morpholinoethylcarbamoyl)phenyl boronic acid as described in example 1 or 30.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846664B2
Source datasetuspto-grants-2014_09
ORD IDord-817a2a8473f54f54926fec4310af673e
Source noteuspto-grants-2014_09