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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80572Generated: October 30, 2026

tert-Butyl 4-acetylbenzoate → tert-butyl 4-[(1S)-1-hydroxypropyl]benzoate

https://huagongshe.com/reaction/80572

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-acetylbenzoateHCID 13844704—
ReactantTert-butyl 4-propionylbenzoateHCID 14226991—
Producttert-butyl 4-[(1S)-1-hydroxypropyl]benzoateHCID 70815235—

Reaction Steps

Instead of the starting material of Reference Example 1, that is, tert-butyl 4-acetylbenzoate, tert-butyl 4-propionylbenzoate was used for a similar procedure as in Reference Example 1 to obtain tert-butyl 4-[(1S)-1-hydroxypropyl]benzoate (compound S3a).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846660B2
Source datasetuspto-grants-2014_09
ORD IDord-edd86a5933194bde8da533b9672e0ce9
Source noteuspto-grants-2014_09