Dichloromethane → 3-(3-(4-Chlorobenzyl)azetidin-1-yl)propan-1-amine

HRID 805897Notes

Reaction equation

HRID 805897 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:12][CH:13]([CH2:15][c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:14]1)([CH3:5])([CH3:6])[CH3:23].[Cl:31][CH2:32][Cl:33].[OH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30]>>[NH2:7][CH2:8][CH2:9][CH2:10][N:11]1[CH2:12][CH:13]([CH2:15][c:16]2[cH:17][cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[CH2:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69411053{3-[3-(4-Chloro-benzyl)-azetidin-1-yl]-propyl}carbamic acid tert-butyl ester

Product 1

HCID 694091233-(3-(4-Chlorobenzyl)azetidin-1-yl)propan-1-amine

Sources & evidence

ORD record
ord-2e3319bf8be24a31b3ffbd1c552fcefd
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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