Dichloromethane → N-(2,2-Dimethylcyclopropanecarbonyl)-DL-norleucine t-butyl ester

HRID 805899Notes

Reaction equation

HRID 805899 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([NH2:8])[CH2:9][CH2:10][CH2:11][CH3:12])=[O:13].[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:21][C:22]1([CH3:28])[CH:23]([C:25](=[O:26])[Cl:27])[CH2:24]1.[Cl:29][CH2:30][Cl:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]([NH:8][C:25]([CH:23]1[C:22]([CH3:21])([CH3:28])[CH2:24]1)=[O:26])[CH2:9][CH2:10][CH2:11][CH3:12])=[O:13]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 110079512,2-Dimethylcyclopropanecarbonyl chlorideHCID 12451445Tert-butyl 2-aminohexanoate

Product 1

HCID 15595771N-(2,2-Dimethylcyclopropanecarbonyl)-DL-norleucine t-butyl ester

Sources & evidence

ORD record
ord-0464a56134564c8f9f85d2cdcf22626e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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