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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80591Generated: October 28, 2026

tert-butyl 2-amino-4-[(1R)-1-({[(6S)-6-(5-chloro-2-methoxybenzyl)-3-methyl-7-oxo-6,7-dihydro-5H-[1,2,4]triazolo[4,3-a][1,4]diazepin-8(9H)-yl]carbonyl}amino)propyl]benzoate → HCID 178456081, compound

https://huagongshe.com/reaction/80591

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl 2-amino-4-[(1R)-1-({[(6S)-6-(5-chloro-2-methoxybenzyl)-3-methyl-7-oxo-6,7-dihydro-5H-[1,2,4]triazolo[4,3-a][1,4]diazepin-8(9H)-yl]carbonyl}amino)propyl]benzoateHCID 86672194—
Reactanttert-butyl 3-[(1R)-1-({[(6S)-6-(5-chloro-2-methoxybenzyl)-3-hydroxy-7-oxo-6,7-dihydro-5H-[1,2,4]triazolo[4,3-a][1,4]diazepin-8(9H)-yl]carbonyl}amino)propyl]benzoateHCID 178456082—
ProductHCID 178456081HCID 178456081—

Reaction Steps

Instead of the starting material of Example 87, Step (3), that is, the compound 87b, the compound 92a was used for a similar procedure as in Example 87, Step (3) to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846660B2
Source datasetuspto-grants-2014_09
ORD IDord-5b18954b1f1a4006ba7ec9dd50f5cc63
Source noteuspto-grants-2014_09