Ethyl Acetate → 1-[5-(3-Methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]cyclohexanecarbonitrile

HRID 805949Notes

Reaction equation

[Br:28][c:29]1[cH:30][n:31][c:32]([C:34]2([C:40]#[N:41])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]2)[s:33]1.[C:42](=[O:43])([O-:44])[O-:45].[CH3:1][c:2]1[cH:3][c:4]([NH:17][c:18]2[n:19][cH:20][cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[n:23]2)[cH:5][c:6]([B:8]2[O:9][C:10]([CH3:11])([CH3:12])[C:13]([CH3:14])([CH3:15])[O:16]2)[cH:7]1.[CH3:48][CH2:49][O:50][C:51]([CH3:52])=[O:53].[Cs+:46].[Cs+:47].[O:56]=[C:57]([CH:58]=[CH:59][c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1)[CH:66]=[CH:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1.[O:74]=[C:75]([CH:76]=[CH:77][c:78]1[cH:79][cH:80][cH:81][cH:82][cH:83]1)[CH:84]=[CH:85][c:86]1[cH:87][cH:88][cH:89][cH:90][cH:91]1.[O:92]=[C:93]([CH:94]=[CH:95][c:96]1[cH:97][cH:98][cH:99][cH:100][cH:101]1)[CH:102]=[CH:103][c:104]1[cH:105][cH:106][cH:107][cH:108][cH:109]1.[Pd:54].[Pd:55]>>[CH3:1][c:2]1[cH:3][c:4]([NH:17][c:18]2[n:19][cH:20][cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[n:23]2)[cH:5][c:6](-[c:29]2[cH:30][n:31][c:32]([C:34]3([C:40]#[N:41])[CH2:35][CH2:36][CH2:37][CH2:38][CH2:39]3)[s:33]2)[cH:7]1