Dichloromethane → 3-(1H-pyrazol-4-yl)-pyridine-2,6-diamine

HRID 806098Notes

Reaction equation

HRID 806098 reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[n:20]1[n:21][cH:22][c:23](-[c:25]2[c:26]([NH2:32])[n:27][c:28]([NH2:31])[cH:29][cH:30]2)[cH:24]1.[CH2:40]([Cl:41])[Cl:42].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[nH:20]1[n:21][cH:22][c:23](-[c:25]2[c:26]([NH2:32])[n:27][c:28]([NH2:31])[cH:29][cH:30]2)[cH:24]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 592554163-(1-Trityl-1H-pyrazol-4-yl)-pyridin-2,6-diamine

Product 1

HCID 592551723-(1H-pyrazol-4-yl)-pyridine-2,6-diamine

Sources & evidence

ORD record
ord-d5ebfbcf669b45ed8453fef4e9ed2b25
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…