Dichloromethane → Benzyl 4-fluoromethyl-4-hydroxy-1-piperidinecarboxylate
Reaction equation
[CH2:21]([Cl:22])[Cl:23].[FH:1].[K:2].[O:3]1[CH2:4][C:5]12[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[CH2:9][CH2:10]2>>[F:1][CH2:4][C:5]1([OH:3])[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:9][CH2:10]1Participants
5
Sources & evidence
- ORD record
- ord-1c680791b7be4bbd9fe157abc9503c60
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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