Tetrahydrofuran → 4-((1-(benzyloxymethyl)-2-phenyl-1H-imidazol-5-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrile

HRID 806392Notes

Reaction equation

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][n:10]1[c:11](-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[n:12][cH:13][cH:14]1.[CH2:26]([CH3:27])[O:28][c:29]1[cH:30][c:31]([O:46][CH:47]([CH3:48])[CH3:49])[c:32]([F:45])[c:33]([CH:34]=[N:35][c:36]2[cH:37][cH:38][c:39]([C:40]#[N:41])[cH:42][cH:43]2)[cH:44]1.[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH:21]([Li:22])([CH2:23][CH3:24])[CH3:25]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][n:10]1[c:11](-[c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[n:12][cH:13][c:14]1[N:35]([CH2:34][c:33]1[c:32]([F:45])[c:31]([O:46][CH:47]([CH3:48])[CH3:49])[cH:30][c:29]([O:28][CH2:26][CH3:27])[cH:44]1)[c:36]1[cH:37][cH:38][c:39]([C:40]#[N:41])[cH:42][cH:43]1