Hydrochloric Acid → 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid

HRID 806434Notes

Reaction equation

HRID 806434 reaction equation
[C:24]([OH:25])([CH3:26])([CH3:27])[CH3:28].[Cl:1][c:2]1[c:3]([CH:8]([C:9]#[N:10])[N:11]2[CH2:12][c:13]3[c:14]([s:17][cH:18][cH:19]3)[CH2:15][CH2:16]2)[cH:4][cH:5][cH:6][cH:7]1.[ClH:20].[K+:23].[OH-:22].[OH2:21]>>[Cl:1][c:2]1[c:3]([CH:8]([C:9](=[O:21])[OH:22])[N:11]2[CH2:12][c:13]3[c:14]([s:17][cH:18][cH:19]3)[CH2:15][CH2:16]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 813Potassium CationHCID 961HydroxideHCID 962WaterHCID 6386tert-ButanolHCID 11369741rac-2-(2-Chlorophenyl)-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetonitrile

Product 1

HCID 41295462-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetic acid

Sources & evidence

ORD record
ord-285d71a2eeee48fdabab772088d7fe76
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…