Dichloromethane → 3-[7-(2,3-Difluoro-phenyl)-4-oxo-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl]-benzonitrile
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([NH:22][C:23]([CH2:24][C:25](=[O:5])[c:27]2[cH:28][c:29]([C:33]#[N:34])[cH:30][cH:31][cH:32]2)=[O:35])[cH:10][c:11](-[c:14]2[c:15]([F:21])[c:16]([F:20])[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1)([CH3:6])([CH3:26])[CH3:36].[Cl:44][CH2:45][Cl:46].[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43]>>[N:7]1=[C:25]([c:27]2[cH:28][c:29]([C:33]#[N:34])[cH:30][cH:31][cH:32]2)[CH2:24][C:23](=[O:35])[NH:22][c:9]2[c:8]1[cH:13][cH:12][c:11](-[c:14]1[c:15]([F:21])[c:16]([F:20])[cH:17][cH:18][cH:19]1)[cH:10]2Participants
4
Sources & evidence
- ORD record
- ord-f36daea8bc3143c082758404a46057ff
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…