Dichloromethane → H-Hyp(Bzl)-OH . HCl

HRID 806619Notes

Reaction equation

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([C:21](=[O:22])[OH:23])[CH2:10][CH:11]([O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[Cl:31][CH2:32][Cl:33].[OH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30]>>[NH:8]1[CH:9]([C:21](=[O:22])[OH:23])[CH2:10][CH:11]([O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 41798284-(Benzyloxy)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid

Product 1

HCID 15927506H-Hyp(Bzl)-OH . HCl

Sources & evidence

ORD record: ord-e6257ff584a341b8b0d0185706b873b4
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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