Palladium → 5-[1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl-N-methylpyridin-2-amine

HRID 806674Notes

Reaction equation

HRID 806674 reaction equation
[Br:13][c:14]1[cH:15][cH:16][c:17]([NH:20][CH3:21])[n:18][cH:19]1.[C:40]([P:41]([C:42]([CH3:43])([CH3:44])[CH3:45])[C:46]([CH3:47])([CH3:48])[CH3:49])([CH3:50])([CH3:51])[CH3:52].[C:53]([P:54]([C:55]([CH3:56])([CH3:57])[CH3:58])[C:59]([CH3:60])([CH3:61])[CH3:62])([CH3:63])([CH3:64])[CH3:65].[CH3:22][O:23][c:24]1[n:25][cH:26][c:27](-[c:28]2[s:29][c:30]3[cH:31][cH:32][cH:33][cH:34][c:35]3[n:36]2)[cH:37][n:38]1.[O:1]1[CH2:2][O:3][c:4]2[cH:5][c:6]3[c:7]([n:8][cH:9][s:10]3)[cH:11][c:12]21.[Pd:39]>>[O:1]1[CH2:2][O:3][c:4]2[cH:5][c:6]3[c:7]([n:8][c:9](-[c:14]4[cH:15][cH:16][c:17]([NH:20][CH3:21])[n:18][cH:19]4)[s:10]3)[cH:11][c:12]21

Participants

6

Reactant 5

HCID 23938PalladiumHCID 83681Tris(1,1-dimethylethyl)phosphine2×HCID 156456635-Bromo-N-methylpyridin-2-amineHCID 20557021[1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazoleHCID 248037262-(2-Methoxypyrimidin-5-yl)-1,3-benzothiazole

Product 1

HCID 248043995-[1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl-N-methylpyridin-2-amine

Sources & evidence

ORD record
ord-9ae131d5a09f469cac3622df242f848f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…