Sodium ion → Dicyclopropyl{5-[3-(morpholin-4-yl)-5-nitrophenyl]-1,3-thiazol-2-yl}methanol

HRID 806724Notes

Reaction equation

HRID 806724 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([C:7]([OH:8])([CH:9]2[CH2:10][CH2:11]2)[CH:12]2[CH2:13][CH2:14]2)[s:6]1.[C:39](=[O:40])([O-:41])[O-:42].[CH3:48][O:49][CH2:50][CH2:51][O:52][CH3:53].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[Cl:45][CH2:46][Cl:47].[N+:15](=[O:16])([O-:17])[c:18]1[cH:19][c:20]([N:33]2[CH2:34][CH2:35][O:36][CH2:37][CH2:38]2)[cH:21][c:22]([B:24]2[O:25][C:26]([CH3:27])([CH3:28])[C:29]([CH3:30])([CH3:31])[O:32]2)[cH:23]1.[Na+:43].[Na+:44]>>[c:2]1(-[c:22]2[cH:21][c:20]([N:33]3[CH2:34][CH2:35][O:36][CH2:37][CH2:38]3)[cH:19][c:18]([N+:15](=[O:16])[O-:17])[cH:23]2)[cH:3][n:4][c:5]([C:7]([OH:8])([CH:9]2[CH2:10][CH2:11]2)[CH:12]2[CH2:13][CH2:14]2)[s:6]1

Participants

8

Reactant 7

HCID 923Sodium ion2×HCID 6344DichloromethaneHCID 80711,2-DimethoxyethaneHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 672568704-(3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)morpholineHCID 67429273(5-Bromothiazol-2-yl)dicyclopropylmethanol

Product 1

HCID 67258049Dicyclopropyl{5-[3-(morpholin-4-yl)-5-nitrophenyl]-1,3-thiazol-2-yl}methanol

Sources & evidence

ORD record
ord-9d4b1d965a7b41f58a4187c0ca7f60c9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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