3-Bromopyridine → 5-(2-chloro-4-methoxyphenyl)-N-(4-ethoxy-1-pyridin-3-ylpyrrolidin-3-yl)-3,6-diethylpyrazin-2-amine
Reaction equation
[Br:1][c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1.[Cl:8][c:9]1[c:10](-[c:17]2[n:18][c:19]([CH2:34][CH3:35])[c:20]([NH:25][CH:26]3[CH2:27][NH:28][CH2:29][CH:30]3[O:31][CH2:32][CH3:33])[n:21][c:22]2[CH2:23][CH3:24])[cH:11][cH:12][c:13]([O:15][CH3:16])[cH:14]1>>[c:2]1([N:28]2[CH2:27][CH:26]([NH:25][c:20]3[c:19]([CH2:34][CH3:35])[n:18][c:17](-[c:10]4[c:9]([Cl:8])[cH:14][c:13]([O:15][CH3:16])[cH:12][cH:11]4)[c:22]([CH2:23][CH3:24])[n:21]3)[CH:30]([O:31][CH2:32][CH3:33])[CH2:29]2)[cH:3][n:4][cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-ee4d247971a546ac96e0b856c0bc93dd
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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