Diisopropylethylamine → 4-[4-[(5-Cyano-furan-2-carbonyl)-amino]-3-(2,5-dimethyl-pyrrol-1-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester

HRID 807169Notes

Reaction equation

HRID 807169 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16](-[n:21]3[c:22]([CH3:27])[cH:23][cH:24][c:25]3[CH3:26])[c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[C:28](#[N:29])[c:30]1[cH:31][cH:32][c:33]([C:35](=[O:36])[Cl:37])[o:34]1.[CH:38]([N:39]([CH2:40][CH3:41])[CH:42]([CH3:43])[CH3:44])([CH3:45])[CH3:46]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16](-[n:21]3[c:22]([CH3:27])[cH:23][cH:24][c:25]3[CH3:26])[c:17]([NH:20][C:35]([c:33]3[cH:32][cH:31][c:30]([C:28]#[N:29])[o:34]3)=[O:36])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 202590395-Cyano-2-furoyl chlorideHCID 68683203HCID 68683203, compound

Product 1

HCID 116988104-[4-[(5-Cyano-furan-2-carbonyl)-amino]-3-(2,5-dimethyl-pyrrol-1-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-6bcef0ad3b8e421ea03d84c1823248a0
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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