Potassium Cation → 4-Chloro-5-(cyclopentyloxy)-2-fluorobenzenamine

HRID 807633Notes

Reaction equation

HRID 807633 reaction equation
[C:11](=[O:12])([O-:13])[O-:14].[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[CH:19]1([Br:24])[CH2:20][CH2:21][CH2:22][CH2:23]1.[I-:18].[K+:15].[K+:16].[K+:17].[NH2:1][c:2]1[c:3]([F:10])[cH:4][c:5]([Cl:9])[c:6]([OH:8])[cH:7]1.[OH2:25]>>[NH2:1][c:2]1[c:3]([F:10])[cH:4][c:5]([Cl:9])[c:6]([O:8][CH:19]2[CH2:20][CH2:21][CH2:22][CH2:23]2)[cH:7]1

Participants

8

Reactant 7

HCID 813Potassium Cation3×HCID 962WaterHCID 6228DimethylformamideHCID 8728BromocyclopentaneHCID 19660Carbonate IonHCID 30165Iodide IonHCID 1586545-Amino-2-chloro-4-fluorophenol

Product 1

HCID 152793894-Chloro-5-(cyclopentyloxy)-2-fluorobenzenamine

Sources & evidence

ORD record
ord-3b89e3fc76c1456482558c7c51abbb9b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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