Tetrahydrofuran → 2-Amino-5-[4-(4-methoxy-phenyl)-imidazol-1-yl]-4-trifluoromethyl-benzoic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([c:4]1[c:5]([N+:27]([O-:28])=[O:29])[cH:6][c:7]([C:23]([F:24])([F:25])[F:26])[c:8](-[n:10]2[cH:11][n:12][c:13](-[c:15]3[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]3)[cH:14]2)[cH:9]1)=[O:30].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[CH3:1][O:2][C:3]([c:4]1[c:5]([NH2:27])[cH:6][c:7]([C:23]([F:24])([F:25])[F:26])[c:8](-[n:10]2[cH:11][n:12][c:13](-[c:15]3[cH:16][cH:17][c:18]([O:21][CH3:22])[cH:19][cH:20]3)[cH:14]2)[cH:9]1)=[O:30]Participants
3
Sources & evidence
- ORD record
- ord-7378641d04da4130b2dccebf22e4d969
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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