Bicarbonate Ion → 1-Cyclohexyl-3-(3,5-dichloro-2',6'-difluoro-4'-hydroxy-biphenyl-4-ylmethyl)-pyrrolidin-2-one
Reaction equation
[B:32]([Br:33])([Br:34])[Br:35].[C:36](=[O:37])([OH:38])[O-:39].[CH2:41]([Cl:42])[Cl:43].[CH:1]1([N:7]2[C:8](=[O:31])[CH:9]([CH2:12][c:13]3[c:14]([Cl:30])[cH:15][c:16](-[c:20]4[c:21]([F:29])[cH:22][c:23]([O:27][CH3:28])[cH:24][c:25]4[F:26])[cH:17][c:18]3[Cl:19])[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[Na+:40]>>[CH:1]1([N:7]2[C:8](=[O:31])[CH:9]([CH2:12][c:13]3[c:14]([Cl:30])[cH:15][c:16](-[c:20]4[c:21]([F:29])[cH:22][c:23]([OH:27])[cH:24][c:25]4[F:26])[cH:17][c:18]3[Cl:19])[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3f8d2ff6470c411ca03b4e52fe988dec
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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