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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 807926Generated: November 2, 2026

Bicarbonate Ion → 1-Cyclohexyl-3-(3,5-dichloro-2',6'-difluoro-4'-hydroxy-biphenyl-4-ylmethyl)-pyrrolidin-2-one

https://huagongshe.com/reaction/807926

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantBoron tribromideHCID 25134—
Reactant1-Cyclohexyl-3-(3,5-dichloro-2',6'-difluoro-4'-methoxy-biphenyl-4-ylmethyl)-pyrrolidin-2-oneHCID 68472468—
Product1-Cyclohexyl-3-(3,5-dichloro-2',6'-difluoro-4'-hydroxy-biphenyl-4-ylmethyl)-pyrrolidin-2-oneHCID 59299423—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3f8d2ff6470c411ca03b4e52fe988dec
Source noteTest data from https://doi.org/10.1039/C8SC04228D