Phosphorus oxychloride → 4-Chloro-2,6-bis-trifluoromethyl-nicotinic acid ethyl ester
Reaction equation
[F:1][C:2]([c:3]1[n:4][c:5]([C:15]([F:16])([F:17])[F:18])[cH:6][c:7]([OH:14])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:19])[F:20].[P:21]([Cl:22])([Cl:23])([Cl:24])=[O:25]>>[F:1][C:2]([c:3]1[n:4][c:5]([C:15]([F:16])([F:17])[F:18])[cH:6][c:7]([Cl:23])[c:8]1[C:9](=[O:10])[O:11][CH2:12][CH3:13])([F:19])[F:20]Participants
3
Sources & evidence
- ORD record
- ord-66fbe90f2338477abb91ac5bdae85c68
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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