HRID808518

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11

1,2-Dichloroethane

C2H4Cl2

HCID66491

1H-Benzo[de]isoquinoline-1,3(2H)-dione

C12H7NO2

HCID522559

N-(2-Chloroethyl)-1,8-naphthalimide

C14H10ClNO2

HCID11138624

tert-Butyl 4-chloropiperidine-1-carboxylate

C10H18ClNO2

HCID11769929

5-Fluoro-3-(piperidin-4-yl)-1H-indole

C13H15FN2

PRODUCTS

产物

HCID15337633

2-[2-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]ethyl]benzo[de]isoquinoline-1,3-dione

C27H24FN3O2

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-17bece93680b4f7ea11fb96ec111a898
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[C:19]1(=[O:20])[c:21]2[c:22]3[c:23]([cH:24][cH:25][cH:26][c:27]3[C:28](=[O:29])[NH:30]1)[cH:31][cH:32][cH:33]2.[C:50]([N:51]1[CH2:52][CH2:53][CH:54]([Cl:55])[CH2:56][CH2:57]1)([O:58][C:59]([CH3:60])([CH3:61])[CH3:62])=[O:63].[Cl:1][CH2:2][CH2:3][N:4]1[C:5](=[O:18])[c:6]2[cH:7][cH:8][cH:9][c:10]3[c:11]2[c:12]([cH:15][cH:16][cH:17]3)[C:13]1=[O:14].[Cl:64][CH2:65][CH2:66][Cl:67].[F:34][c:35]1[cH:36][c:37]2[c:38]([CH:44]3[CH2:45][CH2:46][NH:47][CH2:48][CH2:49]3)[cH:39][nH:40][c:41]2[cH:42][cH:43]1>>[CH2:2]([CH2:3][N:4]1[C:5](=[O:18])[c:6]2[cH:7][cH:8][cH:9][c:10]3[c:11]2[c:12]([cH:15][cH:16][cH:17]3)[C:13]1=[O:14])[N:47]1[CH2:46][CH2:45][CH:44]([c:38]2[c:37]3[cH:36][c:35]([F:34])[cH:43][cH:42][c:41]3[nH:40][cH:39]2)[CH2:49][CH2:48]1