Hydrochloric Acid → 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-3-quinolinecarbonitrile

HRID 808535Notes

Reaction equation

HRID 808535 reaction equation
[Cl:15][c:16]1[c:17]([NH2:18])[cH:19][c:20]([O:24][CH3:25])[c:21]([Cl:23])[cH:22]1.[Cl:1][c:2]1[c:3]([C:13]#[N:14])[cH:4][n:5][c:6]2[cH:7][c:8]([F:12])[cH:9][cH:10][c:11]12.[ClH:26].[n:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[c:2]1([NH:18][c:17]2[c:16]([Cl:15])[cH:22][c:21]([Cl:23])[c:20]([O:24][CH3:25])[cH:19]2)[c:3]([C:13]#[N:14])[cH:4][n:5][c:6]2[cH:7][c:8]([F:12])[cH:9][cH:10][c:11]12

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 14766362,4-Dichloro-5-methoxyanilineHCID 234980814-Chloro-7-fluoroquinoline-3-carbonitrile

Product 1

HCID 234980954-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-fluoro-3-quinolinecarbonitrile

Sources & evidence

ORD record
ord-1c3765ddfda0412a8c26a68ec9b958a6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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