Hydrochloric Acid → 1-Boc-3-fluoro-4-aminopiperidine

HRID 808560Notes

Reaction equation

HRID 808560 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][CH:9]1[CH:10]([F:22])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1.[CH3:24][CH2:25][OH:26].[ClH:23]>>[NH2:8][CH:9]1[CH:10]([F:22])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 21948938Tert-butyl 4-(benzylamino)-3-fluoropiperidine-1-carboxylate

Product 1

HCID 219489521-Boc-3-fluoro-4-aminopiperidine

Sources & evidence

ORD record
ord-6cbb94eeda784ea197302e786208caaa
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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