Potassium Cation → 8-chloro-5-(2-(4-(trifluoromethyl)-6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole

HRID 808616Notes

Reaction equation

HRID 808616 reaction equation
[CH3:31][N:32]1[CH2:33][CH2:34][CH2:35][C:36]1=[O:37].[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([nH:7][c:8]2[cH:9][cH:10]1)[CH2:11][CH2:12][N:13]([CH3:15])[CH2:14]3.[F:16][C:17]([c:18]1[cH:19][c:20]([CH3:26])[n:21][cH:22][c:23]1[CH:24]=[CH2:25])([F:27])[F:28].[K+:30].[OH-:29]>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([n:7]([CH2:25][CH2:24][c:23]4[c:18]([C:17]([F:16])([F:27])[F:28])[cH:19][c:20]([CH3:26])[n:21][cH:22]4)[c:8]2[cH:9][cH:10]1)[CH2:11][CH2:12][N:13]([CH3:15])[CH2:14]3

Participants

6

Reactant 5

HCID 813Potassium CationHCID 961HydroxideHCID 13387N-methyl-2-pyrrolidoneHCID 196158-chloro-2-methyl-1H,2H,3H,4H,5H-pyrido(4,3-b)indoleHCID 68734541Pyridine, 5-ethenyl-2-methyl-4-(trifluoromethyl)-

Product 1

HCID 578763898-chloro-5-(2-(4-(trifluoromethyl)-6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indole

Sources & evidence

ORD record
ord-8909966580224ecda4960a85c6ea56f0
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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