Ammonia → N-(4-Morpholin-4-yl-phenyl)-pyrimidine-4,6-diamine

HRID 808700Notes

Reaction equation

HRID 808700 reaction equation
[CH3:24][OH:25].[Cl:1][c:2]1[cH:3][c:4]([NH2:8])[n:5][cH:6][n:7]1.[NH3:22].[O:9]1[CH2:10][CH2:11][N:12]([c:15]2[cH:16][cH:17][c:18]([NH2:19])[cH:20][cH:21]2)[CH2:13][CH2:14]1.[OH2:23]>>[c:2]1([NH:19][c:18]2[cH:17][cH:16][c:15]([N:12]3[CH2:11][CH2:10][O:9][CH2:14][CH2:13]3)[cH:21][cH:20]2)[cH:3][c:4]([NH2:8])[n:5][cH:6][n:7]1

Participants

6

Reactant 5

HCID 222AmmoniaHCID 887MethanolHCID 962WaterHCID 75655Benzenamine, 4-(4-morpholinyl)-HCID 2380124-Amino-6-chloropyrimidine

Product 1

HCID 66669896N-(4-Morpholin-4-yl-phenyl)-pyrimidine-4,6-diamine

Sources & evidence

ORD record
ord-76ffe215e60f4eb794c642ce2bdba4cc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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