Dichloromethane → 3-(3-Ethoxy-1,2,4-oxadiazol-5-yl)-5-[3-fluoro-4-(trifluoromethoxy)phenyl]piperidine
Reaction equation
[CH2:1]([CH3:2])[O:3][c:4]1[n:5][o:6][c:7]([CH:9]2[CH2:10][N:11]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH2:12][CH:13]([c:15]3[cH:16][c:17]([F:26])[c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]3)[CH2:14]2)[n:8]1.[Cl:41][CH2:42][Cl:43].[OH:34][C:35]([C:36]([F:37])([F:38])[F:39])=[O:40]>>[CH2:1]([CH3:2])[O:3][c:4]1[n:5][o:6][c:7]([CH:9]2[CH2:10][NH:11][CH2:12][CH:13]([c:15]3[cH:16][c:17]([F:26])[c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]3)[CH2:14]2)[n:8]1Participants
4
Sources & evidence
- ORD record
- ord-69581e28a57d41bdbb3a221a4eb02caa
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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