Isopropanol → N-(3-ethynylphenyl)-7-fluoro-6-nitroquinazolin-4-amine
Reaction equation
[C:16](#[CH:17])[c:18]1[cH:19][c:20]([NH2:24])[cH:21][cH:22][cH:23]1.[CH:25]([OH:26])([CH3:27])[CH3:28].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([F:15])[c:9]([N+:12](=[O:13])[O-:14])[cH:10][c:11]12>>[c:2]1([NH:24][c:20]2[cH:19][c:18]([C:16]#[CH:17])[cH:23][cH:22][cH:21]2)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([F:15])[c:9]([N+:12](=[O:13])[O-:14])[cH:10][c:11]12Participants
4
Sources & evidence
- ORD record
- ord-575b04653fad4175a85481f011451454
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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