Tetrahydrofuran → 3-(4-diallylaminomethyl-thiazol-2-yl)-8-fluoro-5-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
Reaction equation
[CH2:25]([CH:26]=[CH2:27])[NH:28][CH2:29][CH:30]=[CH2:31].[Cl:1][CH2:2][c:3]1[n:4][c:5](-[c:8]2[n:9][cH:10][n:11]3[c:12]2[CH2:13][N:14]([CH3:24])[C:15](=[O:23])[c:16]2[c:17]-3[cH:18][cH:19][c:20]([F:22])[cH:21]2)[s:6][cH:7]1.[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[CH2:2]([c:3]1[n:4][c:5](-[c:8]2[n:9][cH:10][n:11]3[c:12]2[CH2:13][N:14]([CH3:24])[C:15](=[O:23])[c:16]2[c:17]-3[cH:18][cH:19][c:20]([F:22])[cH:21]2)[s:6][cH:7]1)[N:28]([CH2:25][CH:26]=[CH2:27])[CH2:29][CH:30]=[CH2:31]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-213969235fbe4c1dab92f8b5a8d232fa
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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