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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 809274Generated: October 26, 2026

4-t-Butylbenzenesulfonyl chloride → 8-Iodo-2-(trifluoromethyl)-6-({4-[1-(trifluoromethyl)cyclopropyl]phenyl}sulfonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine

https://huagongshe.com/reaction/809274

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-t-Butylbenzenesulfonyl chlorideHCID 139882—
Reactant8-bromo-6-[(4-tert-butylphenyl)sulfonyl]-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 59618636—
Reactant8-iodo-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 66901596—
Reactant8-bromo-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 66901653—
Reactant4-[1-(Trifluoromethyl)-cyclopropyl]benzenesulfonyl chlorideHCID 86649040—
Product8-Iodo-2-(trifluoromethyl)-6-({4-[1-(trifluoromethyl)cyclopropyl]phenyl}sulfonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepineHCID 86649039—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-37a564e131bd4b979e21a9e1119d2335
Source noteTest data from https://doi.org/10.1039/C8SC04228D