Potassium Cation → 1-methyl-4-phenyl-N-(phenylmethyl)-4-piperidinecarboxamide

HRID 809278Notes

Reaction equation

HRID 809278 reaction equation
[CH2:25]([N:26]([CH2:27][CH3:28])[CH2:29][CH3:30])[CH3:31].[CH3:1][N:2]1[CH2:3][CH2:4][C:5]([C:8](=[O:9])[Cl:10])([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:6][CH2:7]1.[Cl:38][CH2:39][Cl:40].[K+:32].[K+:33].[O-:34][C:35]([O-:36])=[O:37].[OH2:41].[c:17]1([CH2:23][NH2:24])[cH:18][cH:19][cH:20][cH:21][cH:22]1>>[CH3:1][N:2]1[CH2:3][CH2:4][C:5]([C:8](=[O:9])[NH:24][CH2:23][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:6][CH2:7]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 7504BenzylamineHCID 8471TriethylamineHCID 19660Carbonate IonHCID 219902151-Methyl-4-phenyl-4-piperidinecarbonyl chloride

Product 1

HCID 219902061-methyl-4-phenyl-N-(phenylmethyl)-4-piperidinecarboxamide

Sources & evidence

ORD record
ord-34b1ece20bd84e00aa2b64e01ccfe44d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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