1-Ethylpiperazine → 6'-(4-Ethylpiperazin-1-yl)-6-methyl-2,3'-bipyridine

HRID 80939Notes

Reaction equation

[CH2:1]([N:3]1[CH2:8][CH2:7][NH:6][CH2:5][CH2:4]1)[CH3:2].Cl[C:10]1[N:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([CH3:22])[N:17]=2)=[CH:12][CH:11]=1>>[CH2:1]([N:3]1[CH2:8][CH2:7][N:6]([C:10]2[N:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([CH3:22])[N:17]=3)=[CH:12][CH:11]=2)[CH2:5][CH2:4]1)[CH3:2]

Participants

Reactant 2

HCID 791961-Ethylpiperazine

HCID 86637104HCID 86637104, compound

Product 1

HCID 580065546'-(4-Ethylpiperazin-1-yl)-6-methyl-2,3'-bipyridine

Procedure

The title compound was prepared by a similar procedure to that described in Example 1, starting from 1-ethyl-piperazine and 6′-chloro-6-methyl-[2,3]bipyridinyl.

Sources & evidence

ORD record: ord-8886a04576d34470932e92df6e7d6827
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08846677B2

Reaction notes

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