HRID809535

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID259

Bromide

Br-

HCID8028

Tetrahydrofuran

C4H8O

HCID67970

2-Fluorobenzaldehyde

C7H5FO

结构：CC(C)Cn1c(=O)n(C)c(=O)c2c(Br)c(Cc3ccccc3C(F)(F)F)sc21

HCID11442902

未命名化合物

HCID178461628

未命名化合物

PRODUCTS

生成物

结构：CC(C)Cn1c(=O)n(C)c(=O)c2c(C(O)c3ccccc3F)c(Cc3ccccc3C(F)(F)F)sc21

HCID10208198

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2201eb690af64f22a34010e168f8b58c
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[Br-:29].[Br:1][c:2]1[c:3]([CH2:18][c:19]2[c:20]([C:25]([F:26])([F:27])[F:28])[cH:21][cH:22][cH:23][cH:24]2)[s:4][c:5]2[n:6]([CH2:14][CH:15]([CH3:16])[CH3:17])[c:7](=[O:13])[n:8]([CH3:12])[c:9](=[O:11])[c:10]12.[CH2:30]([Mg+:31])[CH3:32].[F:33][c:34]1[c:35]([CH:36]=[O:37])[cH:38][cH:39][cH:40][cH:41]1.[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[c:2]1([CH:36]([c:35]2[c:34]([F:33])[cH:41][cH:40][cH:39][cH:38]2)[OH:37])[c:3]([CH2:18][c:19]2[c:20]([C:25]([F:26])([F:27])[F:28])[cH:21][cH:22][cH:23][cH:24]2)[s:4][c:5]2[n:6]([CH2:14][CH:15]([CH3:16])[CH3:17])[c:7](=[O:13])[n:8]([CH3:12])[c:9](=[O:11])[c:10]12