HRID809583

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID31275

1,4-Dioxane

C4H8O2

HCID1096407

3-(pyrrolidin-1-ylmethyl)aniline

C11H16N2

HCID57737227

N-{3-[3-(2-chloro-4-pyrimidinyl)-6-methylpyrazolo[1,5-a]pyridin-2-yl]phenyl}-2-(2-thienyl)acetamide

C24H18ClN5OS

PRODUCTS

产物

HCID16749969

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-367fdde283484f019c4a56f14ab5eb2f
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:18]3[cH:19][c:20]([NH:24][C:25]([CH2:26][c:27]4[s:28][cH:29][cH:30][cH:31]4)=[O:32])[cH:21][cH:22][cH:23]3)[n:10][n:11]3[c:12]2[cH:13][cH:14][c:15]([CH3:17])[cH:16]3)[n:7]1.[ClH:46].[N:33]1([CH2:38][c:39]2[cH:40][c:41]([NH2:45])[cH:42][cH:43][cH:44]2)[CH2:34][CH2:35][CH2:36][CH2:37]1.[O:47]1[CH2:48][CH2:49][O:50][CH2:51][CH2:52]1>>[c:2]1([NH:45][c:41]2[cH:40][c:39]([CH2:38][N:33]3[CH2:34][CH2:35][CH2:36][CH2:37]3)[cH:44][cH:43][cH:42]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:18]3[cH:19][c:20]([NH:24][C:25]([CH2:26][c:27]4[s:28][cH:29][cH:30][cH:31]4)=[O:32])[cH:21][cH:22][cH:23]3)[n:10][n:11]3[c:12]2[cH:13][cH:14][c:15]([CH3:17])[cH:16]3)[n:7]1