Ammonia → 1-{4-[3-(8-Amino-1-iodoimidazo[1,5-a]pyrazin-3-yl)cyclobutyl]piperazin-1-yl}ethanone
Reaction equation
[CH:26]([OH:27])([CH3:28])[CH3:29].[Cl:1][c:2]1[c:3]2[n:4]([cH:5][cH:6][n:7]1)[c:8]([CH:12]1[CH2:13][CH:14]([N:16]3[CH2:17][CH2:18][N:19]([C:22]([CH3:23])=[O:24])[CH2:20][CH2:21]3)[CH2:15]1)[n:9][c:10]2[I:11].[NH3:25]>>[c:2]1([NH2:25])[c:3]2[n:4]([cH:5][cH:6][n:7]1)[c:8]([CH:12]1[CH2:13][CH:14]([N:16]3[CH2:17][CH2:18][N:19]([C:22]([CH3:23])=[O:24])[CH2:20][CH2:21]3)[CH2:15]1)[n:9][c:10]2[I:11]Participants
4
Sources & evidence
- ORD record
- ord-23483ea3edc542188c0b961e0c2b4bd6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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