Hydrochloric Acid → N-(3-(4-fluorophenoxy)phenyl)-4-methylpiperidine-4-carboxamide

HRID 809918Notes

Reaction equation

HRID 809918 reaction equation
[ClH:32].[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[C:16]3([CH3:29])[CH2:17][CH2:18][N:19]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:20][CH2:21]3)[cH:10][cH:11][cH:12]2)[cH:30][cH:31]1.[O:33]1[CH2:34][CH2:35][O:36][CH2:37][CH2:38]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[C:16]3([CH3:29])[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[cH:10][cH:11][cH:12]2)[cH:30][cH:31]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 68989388Tert-butyl 4-(3-(4-fluorophenoxy)phenylcarbamoyl)-4-methylpiperidine-1-carboxylate

Product 1

HCID 67036908N-(3-(4-fluorophenoxy)phenyl)-4-methylpiperidine-4-carboxamide

Sources & evidence

ORD record
ord-bf623b6be2414e82af77b2d0ac550203
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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