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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 810188Generated: October 26, 2026

Hydrochloric Acid → 4-(1-(5-Bromopyrimidin-2-yl)piperidin-4-yloxy)-1-(4-cyano-3-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carbonitrile

https://huagongshe.com/reaction/810188

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Reactant2-Chloro-5-cyclopropylpyrimidineHCID 46864087—
Reactant1-(4-Cyano-3-fluorophenyl)-6-oxo-4-piperidin-4-yloxypyridazine-3-carbonitrileHCID 67443961—
Reactant1-(3,4-Dichlorophenyl)-6-oxo-4-piperidin-4-yloxypyridazine-3-carbonitrileHCID 67445587—
Product4-(1-(5-Bromopyrimidin-2-yl)piperidin-4-yloxy)-1-(4-cyano-3-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carbonitrileHCID 44621089—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f5e0af7ceff04bb7aa85f60fc1743434
Source noteTest data from https://doi.org/10.1039/C8SC04228D