1,2-Dichloroethane → 1-Acetyl-4-(4-pyridylaminocarbonyl)piperazine

HRID 810226Notes

Reaction equation

HRID 810226 reaction equation
[C:17]([CH3:18])(=[O:19])[N:20]1[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]1.[Cl:26][CH2:27][CH2:28][Cl:29].[Cl:30][CH2:31][Cl:32].[OH2:33].[n:1]1[cH:2][cH:3][c:4]([NH:7][C:8]([O:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)=[O:16])[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4]([NH:7][C:8](=[O:16])[N:23]2[CH2:22][CH2:21][N:20]([C:17]([CH3:18])=[O:19])[CH2:25][CH2:24]2)[cH:5][cH:6]1

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 962WaterHCID 6344DichloromethaneHCID 837951-AcetylpiperazineHCID 11401617Carbamic acid, 4-pyridinyl-, phenyl ester

Product 1

HCID 98813891-Acetyl-4-(4-pyridylaminocarbonyl)piperazine

Sources & evidence

ORD record
ord-e294e69dfed64fd09faf85d1d67d3aed
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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