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HRID81030

反应详情

EQUATION

反应方程式

HRID 81030 的结构方程式

REACTANTS

反应物

2
结构：O=C(c1ccccc1)c1ccc(B(O)O)cc1
HCID4197235

4-Benzoylphenylboronic acid

C13H11BO3

结构：N#Cc1c(Cl)cncc1Cl
HCID11137599

3,5-Dichloro-4-pyridinecarbonitrile

C6H2Cl2N2

PRODUCTS

生成物

1
结构：N#Cc1c(Cl)cncc1-c1ccc(C(=O)c2ccccc2)cc1
HCID66927492

未命名化合物

收率 80%

PROCEDURE

实验过程

Following conditions described in Step 1 of Example 50, 3,5-dichloroisonicotinonitrile was reacted with 4-benzoylphenylboronic acid to give 3-(4-benzoylphenyl)-5-chloroisonicotinonitrile (˜80% pure). MS (ES+) m/z: 351 (M+H); LC retention time: 3.980 min (analytical HPLC Method A). Step 2: