Hydrochloric Acid → 3-[2-anilino-6-(trifluoromethyl)pyridin-3-yl]-N-[[3-cyano-5-fluoro-4-(methanesulfonamido)phenyl]methyl]prop-2-enamide
Reaction equation
[ClH:17].[NH2:1][CH2:2][c:3]1[cH:4][c:5]([C:15]#[N:16])[c:6]([NH:10][S:11](=[O:12])(=[O:13])[CH3:14])[c:7]([F:9])[cH:8]1.[c:18]1([NH:24][c:25]2[n:26][c:27]([C:36]([F:37])([F:38])[F:39])[cH:28][cH:29][c:30]2[CH:31]=[CH:32][C:33](=[O:34])[OH:35])[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[NH:1]([CH2:2][c:3]1[cH:4][c:5]([C:15]#[N:16])[c:6]([NH:10][S:11](=[O:12])(=[O:13])[CH3:14])[c:7]([F:9])[cH:8]1)[C:33]([CH:32]=[CH:31][c:30]1[c:25]([NH:24][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[n:26][c:27]([C:36]([F:37])([F:38])[F:39])[cH:28][cH:29]1)=[O:34]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e61da58fba2e4d9a94c58d78837e1725
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…