Water → 6-nitro-2,2-dimethyl-3-(trifluoroacetamido)methyl-3,4-dihydro-3-hydroxy-4-(2-oxo-1,2-dihydropyridin-1-yl)-2H-1-benzopyran

HRID 810661Notes

Reaction equation

HRID 810661 reaction equation
[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]2[c:8]([cH:24]1)[CH:9]1[C:10]([CH2:16][NH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23])([C:11]([CH3:13])([CH3:14])[O:12]2)[O:15]1.[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1.[OH2:32].[nH:25]1[c:26](=[O:31])[cH:27][cH:28][cH:29][cH:30]1>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]2[c:8]([cH:24]1)[CH:9]([n:25]1[c:26](=[O:31])[cH:27][cH:28][cH:29][cH:30]1)[C:10]([OH:15])([CH2:16][NH:17][C:18]([C:19]([F:20])([F:21])[F:22])=[O:23])[C:11]([CH3:13])([CH3:14])[O:12]2

Participants

6

Reactant 5

HCID 962WaterHCID 8857Ethyl AcetateHCID 88712-PyridoneHCID 312751,4-DioxaneHCID 19386922HCID 19386922, compound

Product 1

HCID 193871146-nitro-2,2-dimethyl-3-(trifluoroacetamido)methyl-3,4-dihydro-3-hydroxy-4-(2-oxo-1,2-dihydropyridin-1-yl)-2H-1-benzopyran

Sources & evidence

ORD record
ord-c262df300be94c56abe7387747deef66
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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