3-Hydroxybenzaldehyde → 3-{[(3-Chloro-4-fluorophenyl)(2-hydroxy-1-methylethyl)amino]methyl}phenol
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([NH:9][CH:10]([CH2:11][OH:12])[CH3:13])[cH:5][cH:6][c:7]1[F:8].[OH:14][c:15]1[cH:16][c:17]([CH:18]=[O:19])[cH:20][cH:21][cH:22]1>>[Cl:1][c:2]1[cH:3][c:4]([N:9]([CH:10]([CH2:11][OH:12])[CH3:13])[CH2:18][c:17]2[cH:16][c:15]([OH:14])[cH:22][cH:21][cH:20]2)[cH:5][cH:6][c:7]1[F:8]Participants
3
Sources & evidence
- ORD record
- ord-41feca01e5c5448abf7a3652b2b193c2
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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