Hydrochloric Acid → N-[1-benzenesulfonyl-4-(piperidin-4-ylamino)-1H-pyrrolo[2,3-b]pyridin-5-yl]-2-cyano-acetamide

HRID 810845Notes

Reaction equation

[C:2]([O:3][C:4](=[O:5])[N:9]1[CH2:10][CH2:11][CH:12]([NH:15][c:16]2[c:17]3[c:18]([n:19][cH:20][c:21]2[NH:22][C:23]([CH2:24][C:25]#[N:26])=[O:27])[n:28]([S:31](=[O:32])(=[O:33])[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:29][cH:30]3)[CH2:13][CH2:14]1)([CH3:6])([CH3:7])[CH3:8].[CH2:40]1[O:41][CH2:42][CH2:43][O:44][CH2:45]1.[ClH:1]>>[NH:9]1[CH2:10][CH2:11][CH:12]([NH:15][c:16]2[c:17]3[c:18]([n:19][cH:20][c:21]2[NH:22][C:23]([CH2:24][C:25]#[N:26])=[O:27])[n:28]([S:31](=[O:32])(=[O:33])[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:29][cH:30]3)[CH2:13][CH2:14]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 312751,4-Dioxane

HCID 673425034-[1-benzenesulfonyl-5-(2-cyano-acetylamino)-1H-pyrrolo[2,3-b]pyridin-4-ylamino]-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 67379316N-[1-benzenesulfonyl-4-(piperidin-4-ylamino)-1H-pyrrolo[2,3-b]pyridin-5-yl]-2-cyano-acetamide

Sources & evidence

ORD record: ord-6030afe0a54e478c835e56c9795c0253
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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