HCID 178418287, compound → HCID 178461263, compound

HRID 81091Notes

Reaction equation

HRID 81091 reaction equation
[CH3:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([CH2:8][OH:9])[CH2:4][CH2:3]1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH3:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([CH:8]=[O:9])[CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 178418287HCID 178418287, compoundHCID 178461264HCID 178461264, compound

Product 1

HCID 178461263HCID 178461263, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of trans-(4-methylcyclohexyl)methanol (160 g, 1.25 mol) in DCM (1500 mL) was added pyridinium chlorochromate (405 g, 1.88 mol) at 0° C., and the mixture was stirred at room temperature for 2 h. It was filtered and the filtrate was concentrated in vacuo to give trans-4-methylcyclohexanecarbaldehyde.

Workup

  1. filtrationIt was filtered
  2. concentrationthe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-6136ad9f4ef64a878dad3fcff1b70526
Source dataset
uspto-grants-2014_09
Patent number
US08846657B2

Reaction notes

Loading…