Dichloromethane → 2-Amino-2-(7-methoxynaphthalen-2-yl)ethanol

HRID 810913Notes

Reaction equation

HRID 810913 reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:14][CH:15]([CH2:16][OH:17])[c:18]1[cH:19][c:20]2[cH:21][c:22]([O:28][CH3:29])[cH:23][cH:24][c:25]2[cH:26][cH:27]1)([CH3:12])([CH3:13])[CH3:30].[CH2:31]([Cl:32])[Cl:33].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[NH2:14][CH:15]([CH2:16][OH:17])[c:18]1[cH:19][c:20]2[cH:21][c:22]([O:28][CH3:29])[cH:23][cH:24][c:25]2[cH:26][cH:27]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 23573570tert-butyl N-[2-hydroxy-1-(7-methoxynaphthalen-2-yl)ethyl]carbamate

Product 1

HCID 221450172-Amino-2-(7-methoxynaphthalen-2-yl)ethanol

Sources & evidence

ORD record
ord-0a80a168f3b747d7a1c33078b7ca16dc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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