Dichloromethane → 2-amino-5-bromo-N-methoxy-N-methylnicotinamide

HRID 810944Notes

Reaction equation

HRID 810944 reaction equation
[CH3:12][NH:13][O:14][CH3:15].[CH3:16][N:17]1[CH2:18][CH2:19][O:20][CH2:21][CH2:22]1.[Cl:23][CH2:24][Cl:25].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([Br:11])[cH:9][n:10]1>>[NH2:1][c:2]1[c:3]([C:4](=[O:5])[N:13]([CH3:12])[O:14][CH3:15])[cH:7][c:8]([Br:11])[cH:9][n:10]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 79724-MethylmorpholineHCID 14232N,O-DimethylhydroxylamineHCID 7374452-Amino-5-bromonicotinic acid

Product 1

HCID 596997242-amino-5-bromo-N-methoxy-N-methylnicotinamide

Sources & evidence

ORD record
ord-4cb8498f3c504a14bc705d884a34233b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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