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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 811022Generated: November 1, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[(4-methyl-4-oxido-1,4-azaphosphinan-1-yl)methyl]pyridin-2-yl}amino)thiophene-3-carboxamide

https://huagongshe.com/reaction/811022

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant1-[(6-Bromopyridin-2-yl)methyl]-4-methyl-1,4-azaphosphinane 4-oxideHCID 59525655—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[(4-methyl-4-oxido-1,4-azaphosphinan-1-yl)methyl]pyridin-2-yl}amino)thiophene-3-carboxamideHCID 59525836—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-cb0d4efb44f049c3ba9ba11e799b3a75
Source noteTest data from https://doi.org/10.1039/C8SC04228D