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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 811055Generated: November 1, 2026

3-Pyridinemethanamine → 4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-2-[(pyridin-3-ylmethyl)-amino]-6-(2,2,2-trifluoro-ethoxy)-pyrimidine-5-carbonitrile

https://huagongshe.com/reaction/811055

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PyridinemethanamineHCID 31018—
Reactant1,4-DioxaneHCID 31275—
Reactantm-Chloroperbenzoic acidHCID 70297—
Reactant4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-2-methanesulfonyl-6-(2,2,2-trifluoro-ethoxy)-pyrimidine-5-carbonitrileHCID 18753195—
Reactant4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-2-methylsulfanyl-6-(2,2,2-trifluoro-ethoxy)-pyrimidine-5-carbonitrileHCID 18753231—
Product4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-2-[(pyridin-3-ylmethyl)-amino]-6-(2,2,2-trifluoro-ethoxy)-pyrimidine-5-carbonitrileHCID 10299831—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-835019a98607457f836d9422d1d99710
Source noteTest data from https://doi.org/10.1039/C8SC04228D