Hydroxide → 2-[2-(4-Cyclobutyl-piperazin-1-yl)-2-oxo-ethyl]-1,2,3,4-tetrahydro-isoquinoline-6-carboxylic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[CH2:12][N:11]([CH2:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][N:22]([CH:25]3[CH2:26][CH2:27][CH2:28]3)[CH2:23][CH2:24]1)[CH2:10][CH2:9]2.[Li+:29].[OH-:30]>>[O:3]=[C:4]([OH:5])[c:6]1[cH:7][c:8]2[c:13]([cH:14][cH:15]1)[CH2:12][N:11]([CH2:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][N:22]([CH:25]3[CH2:26][CH2:27][CH2:28]3)[CH2:23][CH2:24]1)[CH2:10][CH2:9]2Participants
4
Sources & evidence
- ORD record
- ord-5228bcb5bfe24b7791f32d70e98f25c2
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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